Study on the compatibility of generic drug - Parecoxib Sodium for Injection with its packing materials
SONG Yanjun
PU Xufeng
ZHU Peng
LIU Xiaoshuang
Abstract：Objective To inspect the compatibility of generic drug - Parecoxib Sodium for Injection with its packing materials. Methods By the tests of delamination and migration,positive position and inversions under the influencing factor accelerated tests to observe,determine and compare the changes of the character visible foreign matter insoluble particles, related substances,content for generic drug - Parecoxib Sodium for Injection in their study time. Results No significant differences were found in the delamination and migration tests compared with its early study(P ﹥ 0. 05),and each index was in the acceptable safety threshold;No significant differences were found in each index for samples in positive position and inversions under the influencing factor(P ﹥ 0. 05),in the accelerated treatment(1,2,3 and 6 months)each index for sam-ples of compatibility and stability were found no significant differences(P ﹥ 0. 05). Conclusion The packing materials had good compatibily with the generic drug - Parecoxib Sodium for Injection.
Keywords：Parecoxib Sodium for InjectionInjection vials made of neutral borosilicate glass tubingChlorobutyl rubber closuresCompatibility
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 226-229 )