Drug transporter of liver and its clinical significance research progress
FU Chao
LIU Yang
Abstract:To introduce the function,distribution,and substrate characteristics of drug transporters in the liver and the effect on the treatment of drug in human body disposal process. Based on the liver drug delivery system,and the disposal of the influence in the body to classify and summarize. Liver as an important organ for the metabolism and excretion of endoge-nous and exogenous(drug),except for hepatic enzymes,played an role in the process of metabolism and excretion of the drugs. The efficacy and safety of the drugs would be changed when the function of the transporters was affected.
Keywords:TransportersHepaticDrug - drug interactions
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 731-733,743 )
