The prescription process and quality standard of Yangyin Shengji Membrane
LUO Hui-sheng
KOU Heng-lie
FAN Jing
WANG Xun
Abstract：Objective To study the molding process and quality standard of Yangyin Shengji Membrane. Methods The optimum conditions about molding process of Yangyin Shengji Membrane were optimized by the single factor test and the means of the orthogonal design;The content of berberine hydrochloride was determined by HPLC and its quality standard was established. Results The best molding process of Yangyin Shengji Membrane as follow:the mass ratio of CMC - Na and PVA17 -88 was 2:3,the total mass of CMC - Na and PVA17 -88 in the plasma membrane was 4%,the concentration of the medicine in the plasma membrane was 2. 5%. The linear range of berberine hydrochloride was 2. 62 ~ 13. 1 ng( r = 0. 999 3). The average recovery was 99. 4%,RSD =1. 48%(n =6). Conclusion The screened molding process was stable and reliable. The method of measurement was simple and had good reproducibility and specificity. It can provide a basis for the quality evaluation of Yangyin Shengji Membrance.
Keywords：Yangyin Shengji MembranceMolding processHPLCQuality standardBerberine hydrochloride
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 714-718 )