Comparison of antimicrobial potency of Ceftriaxone Sodium Injection from different manufactures by cup - plate method
GUO Xin-ying
ZANG Heng-chang
WANG Yan-hou
Abstract：Objective To establish a method for comparing the antimicrobial potency of Ceftriaxone Sodium Injection from different manufactures. Methods With the potency determined as response value,the test was designed by the two dose method of antibiotic bioassay cup - plate method in the appendix Ⅺ A of Chinese Pharmacopoeia(edition 2010,part 2),then compared the antibacterial effect of Ceftriaxone Sodium Injection from different factories. Results As to Staphylo-coccus aureus,samples of A,B factories and samples of original research had the same antibacterial effect. As to Escherichia coli,the antibacterial effect was same between the samples of different factories and samples of original research. As to Kleb-siella pneumoniae,the antibacterial effect was no difference between samples from different factories,while the effect of the original research sample was relatively stronger. Conclusion The method could be used for testing the antimicrobial poten-cy of Ceftriaxone Sodium Injection from different manufacturers.
Keywords：Ceftriaxone Sodium InjectionAntimicrobial potencyBiological assayCup - plate method
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 711-713 )