Observation the effect of Cascodex combined with Zoladex on PSA and P540S in metaphase - advanced prostate cancer
LI Zhuo
YE Mu-shi
ZHANG Kang-mei
TANG Wei-xiong
LIU Jian-jun
Abstract：Objective To investigate the safety and feasibility of Cascodex(Biealutamide)combined with Zoladex in metaphase - advanced prostate cancer,and the effect on PSA and P540S. Methods 63 patients with Metaphase - advanced prostate cancer were randomly divided into two groups. The control group was treated with Zoladex,and the observation group was applied with Cascodex and Zoladex after TUPKP and surgical castration. The patient's PSA and P540S in serum were observed. The safety and adverse drug reaction of the method was also evaluated. Results After treatment the PSA and P540S in serum were improved in the both group,showing statistical difference when compared with before treatment(P< 0. 01),and the Inhibit rate of decline in serum PSA and P540S levels in observation group was significantly higher than the control group(P < 0. 01,P < 0. 05). Conclusion Cascodex combined with Zoladex in metaphase - advanced prostate cancer was effective and it can decline the PSA and P540S in serum significantly.
Keywords：CascodexZoladexTUPKPProstate cancer
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 544-546 )