Studies on extraction and purification for piperine from Piper nigrum L.
XU Shi-ming
GUAN Yong-xia
ZHU Xiang-xia
WU Hong-ying
Abstract：Objective To study industrial technology for the extraction and purification of piperine from Piper nigrum L. . Methods Piperine from blacK pepper is extracted and separated with 85% ethanol,and the purity of piperine was det-emined by HPLC. With extraction rate and purity of piperine as index,extraction and purity technology of piperine from Pip-er nigrum L. was optimizied. Results Finally the optimum conditions were extracting and separating piperine from blacK pepper with 85% ethanol by 2 times,ethanol(volume)∶pepper(quality)(10∶1). The filtrate was combined,condensed, and then dynamic cooling crystallization. The crude product of piperine was crystallized many times with anhydrous ethanol. The purity of piperine was more than 98% . Conclusion Extraction and purification technology of piperine used in this study was simple and maneuverability,and the purity of product was high. It was suitable for industrial production.
Keywords：Piper nigrum L.PiperineReflux extractionCrystallizationIndustralization
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 500-502,511 )