Research progress on GLP -1 receptor agonis and DPP -4 inhibitor in treatment of diabetes
LI Na
LI Feng
Abstract：Along with incretin was found,the researches on glucagon - likepeptide - 1(GLP - 1)receptor agonist and dipeptidylpeptidase - 4(DPP - 4)inhibitor have been coming to be the new hot area of researches on diabetes. The article analyzed the pathophysiologic changes of islet cells under the diabetic state,and compared the therapeutic effect and security of GLP - 1 and DPP - 4,in order to provide the reference for chosing GLP - 1 and DPP - 4,especially for those whose pan-creatic islet had nonfunction.
Keywords：GLP - 1 receptor agonisDPP - 4 inhibitorIslet α - cellDiabetes
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 477-479,484 )