Research progress on pharmacological mechanism of LMWH and its clinical indications
LIU Jin-xian
LI Wei-tao
ZHANG Zai-zhong
LI Rong
CHEN Shao-peng
Abstract：Low - molecular - weight heparin(LMWH)is obtained by various methods of fractionation or depolymerisa-tion of polymeric heparin. Compare to unfractionated heparin(UFH),LMWH have relatively smaller molecular weight,better anti - Xa activity,greater bioavailability at low doses,longer half - life and more predictable anticoagulant response when administered in fixed doses. This article described the pharmacological mechanism of LMWH and their clinical indications.
Keywords：Low - molecular - weight heparinAnticoagulationAntithrombosisIndication
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 420-421,424 )