Application in identification of Irbesartan Dispersible Tablets with near - infrared spectroscopy technology
YAN Yan
YIN Guo
LIU Kai-shuang
WANG Jue
WANG Tie-jie
Abstract：Objective To develop methods for rapid identification of Irbesartan Dispersible Tablets by Near - infrared (NIR)spectroscopy analytical technology and chemometrics. Methods NIR spectrum of Irbesartan Dispersible Tablets were collected by a fiber optic probe. The conformity test model was performed by comparing consistency index(CI)value and CI limit. The quick compare model was established through the correlation coefficient method. Results The conformity test model and quick compare model can rapidly identify and accurately distinguish Irbesartan Dispersible Tablets(manufac-tured by A)from similar products of other manufacturers. The CI value of the validation samples from other manufactures beyond the limit of 7. 0. Compared with the reference sample,the correlation coefficient(R2 )were less than 97% . Conclu-sion The NIR methods were simple and rapid,which can be used in quick identification of Irbesartan Dispersible Tablets (manufactured by A)in mobile lab.
Keywords：Irbesartan Dispersible TabletsNear - infrared(NIR)spectroscopyConformity testCorrelation coeffi-cientQuick identification
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 384-386 )