Study on the quality standard of Guipi Pills
GAO Hui
LI Xiao-yan
LI Bing
LIN Xiao
Abstract：Objective To improve the quality standard of Guipi Pills for better controlling the quality of drugs. Meth-ods The TLC was employed on Radix Astragali,honey-fried Radix Astragali,Radix Polygalae,Radix Angelicae Sinensis for identification;The content of astragaloside in Radix Astragali was determined by HPLC-ELSD. A Dikma Diamonsil C18 column(4. 6 mm × 250 mm,5 μm)was adopted with methanol-water(32:68)as mobile phase at a flow rate of 1 mL· min-1 . An eweaporative light-scattering detector( ELSD)Model 2000 was used with the drift tube temperature at 105 ℃and the gas flow rate at 2. 5 L·min-1 . Results The TLC chromatographic spots were clear;The linear range of astragalo-side was 1. 046 0~5. 230 0 μg(r=0. 999 8),the average recovery was 101. 24%,and RSD=1. 92%(n=6). Conclusion The results showed that this method was accurate,reliable and can be used for the preparation of quality control.
Keywords：Guipi PillsThin-layer chromatographyHPLC-ELSD
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 276-279 )