Resarch of online control of NIRS in the Radix paeoniae alba water extraction process
ZHANG Hui
HU Tian
ZANG Heng-chang
Abstract:To study a online analysis method of Radix paeoniae alba extraction process of Shenzhiling Oral Liquid with NIRS. Methods The study carried on under laboratory scale,recording near infrared spectroscopy of samples by using the ANTARIS II near infrared spectrometer and HPLC method was applied for determining paeoniflorin content in the sample. In order to establish quantitative analysis model,the spectral data and liquid phase data were fit by PLS. Results The study showed that the spectra based on OSC with mean center can obtain a good model in the optical spectrum and the model pa-rameters:RMSEC,R2cal ,R2val ,LVs were 0. 080 5,0. 968 4,0. 920 6,4,respectively. Conclusion This experiment of Radix paeoniae alba water extraction process of Shenzhiling Oral Liquid provided a new online monitoring method,and then provid-ed protection for the stability of product and the product quality.
Keywords:NIRSRadix paeoniae alba water extraction processPaeoniflorinQuantitative analysisShenzhiling Oral Liquid
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 272-275 )
Journal of Pharmaceutical Research

Journal of Pharmaceutical Research

ISSN:2095-5375
Year, Vol.(Issue):2015,(5)