Study on the main comPonents of the Dachuanxiong TabIets based on muItiPIe waveIength coverage fusion fingerPrint
TANG shuang
BAO Yongrui
MENG Xiansheng
FU Li
WANG shuai
Abstract：Pbjective To set up the multi—wavelength fusion HPLC fingerprint of 10 batches of the Dachuanxiong Tablets,common peaks were preliminary identified on that basis,building the total analyzed fingerprint in order to provide a base for the comprehensive quality controlling of the drug. Methods The fingerprint under different wavelength for ten bat-ches of Dachuanxiong Tablets were tested by HPLC — DAD and the active components was identified by HPLC —MS. ResuIts A HPLC fingerprinting pattern of 10 batches of the Dachuanxiong Tablets was set up based on multi—wave-length fusion,which demarcated 13 common peaks,8 of which were confirmed,the similarity was more than 0. 92 between the correlation coefficients of the 10 samples. ConcIusion In this article,with the method of multi—wavelength fusion and HPLC—MS,we established the total analyzed fingerprint of Dachuanxiong Tablets and provided the foundation for the quali-ty controlling of the tablets,which laying a foundation to regulate traditional Chinese medicine preparations and its reasona-ble application.
Keywords：Dachuanxiong TabletsMultiple wavelength fusionFingerprintHPLC-MS
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 7-9,22 )