Study on the dynamic change of rutin content in mulberry leaves
WANG Zheng
SHEN Hua
LI Lei
LI Hong-yan
Abstract:Objective To study the content of rutin in different period of mulberry leaf. Methods The Kromasil C18 column(4. 6 mm × 250 mm,5μm)was used,and mobile phase was composed of methanol-0. 5% phosphoric acid solution ( gradient elution),Detection wavelength was at 358 nm,the column temperature was at 30℃. Results The linear range of rutin was 0. 126 2~2. 02 μg( r=0. 999 9). The average recovery of rutin was 97. 88%,the highest content of rutin in mul-berry leaves before and after the frost. Conclusion Preliminary results suggested that rules of rutin in mulberry leaves sea-sonal changes.
Keywords:Mulberry leavesRutinHPLCDetermination
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 693-695 )
Journal of Pharmaceutical Research

Journal of Pharmaceutical Research

ISSN:2095-5375
Year, Vol.(Issue):2014,(12)