Improved synthesis of S - pantoprazole sodium
LU Jin-cheng
Abstract：With 2 - methyl - 3,4 - dimethoxy pyridine as raw material,2 - chloromethyl - 3,4 - two dimethoxy pyri-dine hydrochloride was obtained after chloridating of ammonium chloride and then carried out of condensation reaction with 5 - two difluoro methoxy - 2 - sulfo - 1H - benzimidazole. S - pantoprazole was synthesized by asymmetric oxidation,then salified by sodium hydroxide to gain S - pantoprazole sodium.
Keywords：S - pantoprazole sodiumSynthesisAsymmetric oxidation
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 617-618 )