Clinical efficacy of traditional Chinese medicine compound granules in NAFLD
JI Le-jun
GAO Xi-zhang
ZHAO Fu-mei
JIA Xiao-chen
Abstract：The paper examined the clinical efficacy of chinese medicine compound granules in treatment of non - alco-holic fatty liver disease using randomized,double - blind,placebo - control and multi - center clinical trials,and evaluated its effectiveness and safety. The subjects compliance was good. The main outcome indicators of liver/ spleen CT ratio in-creased. The treatment group effective rate was 67. 57% ,and the placebo group effective rate was 39. 09% . The difference was statistically significant(P = 0. 000 0). Secondary efficacy index TCM symptoms integral value was reduced. The experi-mental group decreased by 5. 64 ± 3. 79,and the placebo group decreased by 3. 32 ± 2. 87. The difference was statistically significant(P ﹤ 0. 000 1). The incidence of adverse reactions of experimental group was 1. 8% ,no statistically significant difference(P = 0. 497 7)compared with the placebo group. In the process of tested drug or placebo,no serious adverse e-vents in subjects.
Keywords：Non - alcoholic fatty liver diseaseCompoundTraditional Chinese medicine granulesClinical efficacy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 419-421,424 )