Determination of residual organic solvents in daptomycin by headspace gas chromatography
LIU Shi-juan
HAO Gui-zhou
XU Jian
Abstract:Objective To establish a method for the determination of residual ethanol and acetonitrile in daptomycin by headspace gas chromatography. Methods The DB - WAX capillary column was adopted,temperature programming and FID detector was used. Results The two compositions had good linear relationship and the precision and reproducibility of the method were in accord with the requests. Conclusion This method could be used to determine residual ethanol and acetonitrile in daptomycin.
Keywords:Headspace gas chromatographyDaptomycinresidual solventsDetermination
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 389-390,410 )
