Effect of Fufang Danshen Tablets on static bone histomorphology parameters of cancellous bone tissue in CIA rats
XIAO Yan-shen
DONG Wen-ming
WANG Ya-hai
Abstract：Objective To study the effect of Fufang Danshen Tablets against osteoporosis of CIA rats. Methods CIA rat model was established by injecting bovine type II collagen subcutaneously. Three groups including normal control group (n = 10),experimental control group(n = 12)and experimental group(n = 12)were built and the mice were treated with sterilized water or Fufang Danshen Tablets,respectively for 2 months. Parameters including wet weight,dry weight,length and circumference,as well as the static bone histomorphology parameters of the mice shin bone in each group were collected for analysis. Results The wet weight,dry weight and static bone histomorphology parameters of bone tissue in experimental and experimental control group were significantly lower than that in normal control group,the similar results were found be-tween experimental control group and experimental group. Conclusion Fufang Danshen Tablets can obviously inhibit bone erosion and osteoporosis in CIA rats,but further study was needed for clarifying the mechanism.
Keywords：Fufang Danshenrheumatoid arthritisOsteoporosisCIA
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 379-381,388 )