Research progress on Btk inhibitors
DENG Rong
ZHAO Li-zhi
Abstract：Btk is necessary in B-cell antigen receptor( BCR)signaling pathway and cytokine-induced signal pathway in the macrophages. Btk inhibition has emerged as an attractive target for therapeutic intervention in human B-cell malig-nancies and autoimmune disorders. This review summarized the mechanism of Btk inhibitors and recent developments of Btk inhibitors already launched or in clinical trial.
Keywords：BtkB-cellLymphomaRheumatoid arthritis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 359-361,372 )