Research progress on strategies and methods for detecting hydrogen sulfide by surface-enhanced Raman spectroscopy
ZHU Xiaoyu
WAN Lin
ZHANG Qian
YANG Yamin
ZHANG Yizhi
Abstract：Hydrogen sulfide(H2 S)as an important gas signaling molecule,is widely involved in various physiological and patho-logical processes of living organisms.Surface-enhanced Raman spectroscopy(SERS)technology with its advantages of high sensitivity,high specificity and resistance to photobleaching,has shown great potential in the field of H2 S detection.This paper systematically re-views the research progress of H2 S detection based on SERS technology in the past years,with a focus on the innovative research in di-rect detection strategies,molecular-mediated indirect detection strategies,SERS combined with other technologies,and the construc-tion methods of SERS active substrates.Finally,the challenges currently faced in the field are summarized and the future development directions are prospected.
Keywords：Surface-enhanced Raman spectroscopy technologyHydrogen sulfideNanobiosensorGasotransmitterMolecular detection
Publication Date：2026-04-30
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：7( 168-174 )