Development of an EIT-EEG synchronous detection system and feasibility study for epileptic zone localization
ZHU Wenjing
WU Xinyu
YANG Jingrong
CHEN Cheng
WU Guan
YANG Fang
WANG Lei
Abstract：Regarding the problem for precise localization of refractory epileptic nidus,we developed an electrical impedance tomo-graphy(EIT)and electroencephalogram(EEG)synchronous detection system to verify the feasibility and accuracy of EIT in the localiza-tion of epileptogenic zone(EZ).The system employed the same set of electrodes to achieve simultaneous,synchronous and co-channel acquisition of impedance and EEG signals.The dual-domain collaborative strategy of"hardware low-pass+software comb"was used to eliminate mutual interference between devices,and ensure the accuracy of signal acquisition.The test results on 20 healthy adult male SD rats showed that the average deviation between EIT-localized and EEG-topography centroids was 0.13 mm,with a 6.37%rel-ative error.Moreover,the area was confirmed by histopathology to have typical features of epileptic lesions,indicating that EIT has the feasibility of accurately locating EZ.The research can offer a new method for precise EZ localization and significance for improving the success rate of epilepsy treatment.
Keywords：Electrical impedance tomographyElectroencephalogramSynchronous detection systemEpileptogenic zone localiza-tionFilter
Publication Date：2026-02-28
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：8( 7-14 )