Blood flow simulation in patients with atrial fibrillation before and after left atrial appendage occlusion based on CT image
XU Qinghu
ZHANG Tianyi
CHENG Yunzhang
Abstract：To investigate the hemodynamic changes of patients before and after left atrial appendage occlusion,we established a computational fluid dynamics(CFD)model before and after occlusion of the left atrial appendage based on CT images and perform nu-merical simulation.Firstly,a three-dimensional model was reconstructed by using CT images of patients with atrial fibrillation.Then,hemodynamic numerical simulation was performed on the CFD model.Hemodynamic parameters such as blood flow velocity,time aver-age wall shear stress(TAWSS)and oscillation shear index(OSI)were obtained and compared before and after occlusion.Simulation results showed that the left atrial ear could improve the state of intra-atrial blood flow disorder,and improve the distribution of TAWSS and OSI on the atrial wall,which could effectively reduce the risk of thromboembolism in patients to a certain extent.It can provide some theoretical support for clinical medicine.
Keywords：Left atrial appendage occlusionComputational fluid dynamicsHemodynamic characteristicsAtrial fibrillationCT image
Publication Date：2023-12-25
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：6( 356-361 )