Preparation of Homocysteine Electrode and the Study of Determined Performance
JIANG Shuqing
BO Hui
LIU Kuanhao
LI Kun
Abstract：To develop a new method for determination of homocysteine in plasma.A homocysteine(HCY)ion selective electrode was fabricated with a molecularly imprinted polymer (MIP).The process was based on the synthesis of polymers with HCY as tem-plate,α-methacrylic acid (MAA)as functional monomer,and ethylene glycol dimethacrylate (EGDMA)as a crosslinker,2,2′-Azobis(2 -methylpropionitrile)(AIBN)as initiator.The ion selective electrode was prepared with this HCY MIP as electric active substance,and was used to assay the HCY in plasma.The electromotive force (E)exhibited a excellent Nernst response to HCY con-centration over a range of 5 ×10 -3 mol/L ~5 ×10 -5 mol/L,and average recovery rate was 101.3%.RSD was 2.71% .The HCY e-lectrode can be used for determintion of real sample.
Keywords：HomocysteineElectrodeDirect potential methodNernst
Publication Date：2016-01-01
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：4( 205-208 )