Research on the pO2 and Weak Fluorescence Monitoring and Imaging System in Photodynamic Therapy
HUANG Dong
LI Weitao
WANG Hongke
QIAN Zhiyu
Abstract：Since the key multiple parameters need to be monitored during the photodynamic therapy (PDT)in deep tumor,we de-veloped a pO2 and weak fluorescence monitoring and imaging system.The Princeton Instrument scientific -grade CCD was used as the fluorescence imaging detector,NeoFox of Ocean Optics as O2 sensor and LabVIEW as programming platform.The function of the sys-tem included the fluorescence image measurement,the pO2 data acquisition,the fluorescence intensity detection,result display,data analyzing and recording simultaneously.The system realized the real -time multiple parameters measurement and analysis during PDT. The PDT chemical reaction experiments validate the sensitivity of system,which has a potential for assessment of PDT.
Keywords：Photodynamic therapy(PDT)Partial pressure of oxygenWeak fluorescence imagingreal -time monitorTherapy evaluation
Publication Date：2015-01-01
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：5( 139-143 )