Compatibility of Penicillin Sodium in the PVC Infusion
SHEN Yong
PAN Huaxian
LIU Aijuan
Qin Yang
LI Wenli
WU Changyan
Abstract：To analyze the leaching content from disposable infusion by simulating clinical use of Penicillin sodium injection.We used type A and B infusion from two different manufacturers.Drug adsorption and compound migrating were not found using HPLC. However,after the detection of GC-MS,cyclohexanone and DEHP were found in both of the two infusions,little isooctanol was also found in infusion A.These leaching contents were all introduced by the manufactor of the infusion,and the doses were far below the in-take of human body.This research shows that the use of disposable infusion for Penicillin sodium in clinical treatment takes a lower risk.
Keywords：Disposable infusionLeaching contentPenicillin sodiumDiethylhexyl Phthalate(DEHP)
Publication Date：2015-01-01
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：6( 58-63 )