Preparation and Biocompatibility Investigation of the Absorbable Polysaccharide Microspheres
JIANG Lijuan
LI Ling
ZHANG Chunxia
SONG Xiang
ZHANG Linlin
LIU Changfeng
Abstract：The absorbable polysaccharide microspheres is made of potato starch by emulsion and cross-linking,which is a kind of novel biodegradable hemostatic materials with microporous structure.The absorbable polysaccharide microspheres was studied by using the subcutaneous reactivity,sensitization,acute systemic toxicity,intramuscular implantation tests described in GB/T16886.The ex-perimental results showed that the microporous polysaccharide microspheres had no subcutaneous reactivity,no sensitization,no acute systemic reaction,no solids and obvious tissue reaction observed after 2 weeks implantation.It is concluded that the absorbable poly-saccharide microspheres has excellent biocompatibility and meets the requirement for clinical application.
Keywords：MicrospheresSubcutaneous reactivitySensitizationIntramuscular implantation testsBiocompatibility
Publication Date：2014-01-01
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：3( 32-34 )