Development and Evaluation of Absorbable Anti-adhesion Film
LIU Jianjian
FENG Xiaoyi
ZHANG Yan
LI Chao
GUO Xueping
Abstract：To prepare and evaluate the absorbable anti-adhesion film.Hyaluronic acid (HA)and hydroxyethyl cellulose (HEC) were used as main raw material,while the orthogonal design was adopted to optimize the preparation process with HA molecular weight, HA-HEC ratio,crosslinker concentration as study factors.The optimal preparation conditions were as follow:2000 kD HA,HA/HEC 1/1 ,crosslinker concentration was 0.5 μl/mL.Moreover,this film was effective for rat model in anti-adhesion.The absorbable anti-adhesion film with enough mechanical strength can play an attractive role in anti-adhesion.
Keywords：Hyaluronic acidHydroxyethyl celluloseOrthogonal designAbsorbableAnti-adhesion
Publication Date：2013-01-01
Online Publishing Date：2026-09-11(First online date of this platform, not the publication date of the document)
Pages：4( 180-183 )