Meta Analysis of Anticoagulant Drugs for Prevention of PICC Associated Thrombosis
Abstract：Objective:To investigate the application of anticoagulant therapy in patients with PICC catheter by meta analysis ,and to pro-vide evidence for the prevention of venous thrombosis after catheter placement .Method:Randomized controlled trials(RCT)on the effect of anticoagulant therapy on the prevention of venous thrombosis in patients with PICC catheter were retrieved by using the computer to search the Cochrane Library,PubMed,China biomedical database(CBM),China Journal Full-text Database(CNKI)from 2000 to 2016.The litera-ture was selected according to the evaluation method of evidence-based medicine system ,and was analyzed by Cochrane software RevMan 5.3.Results:We included 10 randomized controlled trials ,a total of 2269 cases of patients with PICC catheter .The results of Meta analysis showed that the PICC catheter in patients with anticoagulant drug prevention can effectively reduce the incidence of catheter -related throm-bosis(RR=0.24,P<0.01);the results of two trials showed that there was a significant difference between two groups in prolonging the duration of PICC treatment(P<0.01).Conclusion:Anticoagulant therapy for PICC patients during catheter placement can effectively pre -vent catheter related thrombosis ,prolong the duration of PICC stay ,and reduce adverse reactions.
Keywords：PICCThrombosisAnticoagulantMeta analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 4-7 )