Observation on the anticoagulative effect of regional citrate anticoagulation for hemoperfusion in patients with acute poisoning
Abstract：Objective:To investigate the anticoagulative effect of regional citrate anticoagulation for hemoperfusion in patients with acute poisoning. Methods:37 acute poisoning patients who would receive hemoperfusion were randomly divided into group A(anticoagulation with unfractionated heparin),group B(anticoagulation with low molecular weight heparin)and group C(anticoagulation with local sodium cit-rate). The count of platelet,activated partial thromboplastin time and coagulation in hemofilter and bleeding were monitored and evaluated for all cases. Results:The differences in the comparison of the blood coagulation,bleeding,coagulation function and platelet count in group C with group A and B were statistically significant(P ﹤ 0. 05). Conclusion:The effect of citrate might be better at anticoagulation than hep-arin in hemoperfusion for acute poisoning patients.
Keywords：Acute poisoningHemoperfusionAnticoagulantHeparinCitrate
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 26-27 )