A study on the change of cerebral blood flow in premature infants with intracranial hemorrhage

Wang Xingang; Yang Ning

doi:10.3969/j.issn.1006-7256.2015.15.008

Abstract：Objective:To observe the ultrasonographic features of the periventricular-intraventricular hemorrhage ( PIVH) in prema-ture infants and evaluate the value of early diagnosis of PIVH. Methods:100 premature infants were divided into the experimental group ( n=77) and the control group (n=23) according to cranial ultrasound examination results. The premature infants in both groups were given the same routine drug treatment. The premature infants in the experimental group were further divided into the severe group (n=12) and the mild group (n=65) according to the severity of bleeding. The ratio of the peaK systolic blood flow velocity and diastolic velocity (S/D) and the resistance index (RI) were measured with the cranium chromatic ultrasound on the 3rd and 10th day after premature infants were born. Results:The smaller the gestational age was,the higher the incidence of intraventricular hemorrhage was;the lighter the birth weight was,the higher the incidence and degree of intraventricular hemorrhage was;the S/D value and RI level was significantly higher in the experimental group than the control group on the 3rd day after born (P<0. 01),wherein,S/D value and RI level was higher in the se-vere group than the mild group (P<0. 01);S/D value and RI level in the mild group has been restored to the level of the control group on the 10th day after born (P>0. 05);S/D value and RI level was higher in the severe group than the mild group and the control group (P<0. 01);S/D value and RI level significantly decreased on the 10th day after born compared with that on the 3rd day after born in the mild and severe groups (P<0. 05). Conclusion:The smaller and the lighter the gestational age and the birth weight is,the higher the inci-dence of PIVH is. The routine cranial ultrasound examination can maKe an early diagnosis of PIVH in preterm infants so as to conduct timely clinical intervention.