Observation on the effect of intravenous supply of iron in large dose combined with the usage of erythropoietin in the correction of renal anemia of patients with peritoneal dialysis
Chen Juanjuan
Xing Xiaohong
Zhang Xiaoping
Abstract：Objective:To observe the clinical effect of intravenous supply of iron in large dose combined with the usage of erythropoietin in the correction of renal anemia of patients with peritoneal dialysis and nursing measures. Methods:200 patients with renal anemia caused by long - term peritoneal dialysis were randomly divided into the control group and the observation group(100 cases in each group). The patients in the control group were treated with oral Ferrous Succinate tablets and the patients in the observation group were intravenously given Iron Dextran in large dose;at the same time the patients in both groups were given subcutaneous injection of recombinant human erythropoietin(EPO)of 10 000 U per week and the course of treatment was 2 months. The clinical effect,safety and adverse reactions were observed and compared between the two groups. Results:After the treatment,indexes like hemoglobin,red blood cell count,hematocrit,ser-um iron,serum ferritin and transferrin saturation were significantly increased in the two groups(P < 0. 05),and the improvement of the pa-tients was significantly better in the observation group than the control group(P < 0. 05). Conclusion:The clinical effect of intravenous supply of iron in large dose combined with the usage of erythropoietin is better than oral treatment with Ferrous Succinate tablets in the cor-rection of renal anemia of patients with peritoneal dialysis,and at the same time close observation on patient's condition and corresponding nursing measures can reduce the adverse reactions of the treatment.
Keywords：Peritoneal dialysisIntravenous supply of ironRecombinant human erythropoietinRenal anemiaNursing
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 31-33 )