Application of deZocine combined with propofol to painless induced abortion

Shen Heyuan

doi:10.3969/j.issn.1006-7256.2014.18.004

Abstract：Objective:To explore the application of dezocine combined with propofol and nursing methods in painless induced abortion. Methods:285 pregnant women scheduled for painless induced abortion were randomly divided into the observation group(n=148)and the control group(n=137). The pregnant women in the observation group were given 5 mg dezocine diluted in 5 ml,and then given propofol (1~2 mg/kg)one minute later,completing injection in 30~60 seconds. The operation started as soon as the eyelash reflex of the preg-nant women disappeared. The pregnant women in the control group were given injection of sodium chloride 5 ml plus propofol 1 to 2 mg/kg. SBP,DBP,HR and SpO2 of the pregnant women before given drug(T1),in operation(T2)and when they opened eyes(T3),the total dose of propofol in operation,awakening time and the length of stay in hospital,incidence of adverse reactions and satisfaction of obstetri-cian were compared between the two groups. Results:SBP in operation was obviously lower in the control group than the observation group (P〈0. 05);the total dose of propofol in the control group was significantly more than that in the observation group and the awakening time,the length of stay in hospital was significantly longer in the control group than the observation group(P〈0. 01). Conclusion:Dezo-cine combined with propofol used in the anesthesia for painless induced abortion can enhance the analgesic effect,attenuate nociceptive re-sponses and decrease the dose of propofol and adverse reaction.