Effect of compound SMZ combined with berberine on the injury of skin of nasopharyngeal cancer patients with radiotherapy
Abstract：Objective:To investigate the effect of compound SMZ combined with berberine on the injury of skin of nasopharyngeal cancer patients with radiotherapy .Methods:76 nasopharyngeal cancer patients were randomly divided into the experimental group and the control group (38 cases in each group).Povidone iodine was daubed around the irradiation field of the patient 's neck in the control group;com-pound SMZ combined with berberine was used in the experimental group .First-degree radioactive skin injury of the patients in different time-range and the degree of skin injury on the 6th week of radiotherapy were compared between the two groups .Results:There were sta-tistically significant differences in the comparison of first -degree radioactive skin injury in different time -range and the degree of skin in-jury on the 6th week of radiotherapy between the two groups (P<0.05).Conclusion:The local preventive intervention measures can reduce the radiation injury of skin of radiotherapy in patients with nasopharyngeal cancer .The compound SMZ combined with berberine has a pro-tective effect on the patient's skin in radiotherapy .
Keywords：Nasopharyngeal cancerRadiotherapyRadiation dermatitis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 14-15,16 )