Application of the modified adsorption method in heparin-free dialysis to HD patients with high-risk bleeding tendency

Xie Jingchen

doi:10.3969/j.issn.1006-7256.2014.06.010

Abstract：Objective:To explore the application of the modified adsorption method in heparin-free dialysis to hemodialysis( HD) pa-tients with high-risk bleeding tendency.Methods:69 maintenance HD patients were randomly divided into the observation group(n=37) and the control group(n=32).The traditional saline flushes method was used in the control group and the modified adsorption method combined with saline flushes method was used in the observation group.The blood coagulation function,biochemical indicators,effective treatment time,saline flushing quantity,ultrafiltration volume,pipeline and dialyser coagulation,the time of hemostasis by compression on puncture point and the occurrence of new bleeding were compared between the two groups.Results:There were statistically significant differences in the comparison of the blood coagulation function,biochemical indicators,effective treatment time,saline flushing quantity and ultrafiltration volume between the two groups(P<0.05);the degree of pipeline and dialyzer coagulation was mainly in level 0 and level I in the observation group,accounting for 69.41%;in level II and III in the control group,accounting for 65.93%( P<0.05);no new hem-orrhage in both groups,the comparison of hemostasis time at arterial and venous end was not significantly different between the two groups (P>0.05).Conclusion:The modified adsorption method combined with saline flushes method does not affect the coagulation function of HD patients high-risk bleeding tendency,but it can reduce or mitigate the coagulation degree during extracorporeal circulation,prolong the effective treatment time and is conducive to the removal of the solute.