New insights into estrogenic regulation of O6-methylguanine DNA-methyltransferase (MGMT)in human breast cancer cells:Co-degradation of ER-α and MGMT proteins by fulvestrant or O6-benzylguanine indicates fresh avenues for therapy

Ameya Paranjpe; Nathan I.Bailey; Santhi Konduri; George C.Bobustuc; Francis Ali-Osman; Mohd.A.Yusuf; Surendra R.Punganuru

doi:10.7555/JBR.30.20160040

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Home>Articles>New insights into estrogenic regulation of O6-methylguanine DNA-methyltransferase (MGMT)in human breast cancer cells:Co-degradation of ER-α and MGMT proteins by fulvestrant or O6-benzylguanine indicates fresh avenues for therapy

DOI: 10.7555/JBR.30.20160040

New insights into estrogenic regulation of O6-methylguanine DNA-methyltransferase (MGMT)in human breast cancer cells:Co-degradation of ER-α and MGMT proteins by fulvestrant or O6-benzylguanine indicates fresh avenues for therapy

Ameya Paranjpe

Nathan I.Bailey

Santhi Konduri

George C.Bobustuc

Francis Ali-Osman

Mohd.A.Yusuf

Surendra R.Punganuru

Keywords：estrogen signalingMGMT DNA repairubiquitin-proteasome pathwaybreast canceranti-estrogens

Publication Date：2016-01-01

Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)

The Journal of Biomedical Research

ISSN：1007-4368

Year, Vol.(Issue)：2016,30(5)