Improved Method for Pancreaticoduodenal Transplantation in Rat Model
ZHU Jun
XU Ze-kuan
MIAO Yi
Abstract：Objecave: To improve the method of pancreaticoduodenal transplantation and to establish a more physiological rat model. Methods: SD rats served as donors and recipients. The vein was reconstructed by end-to-side anastomosis between the donor portal vein and the recipient superior mesenteric vein, and arterial reconstruction was carried out by end-to-side anastomosis of the donor to the recipient abdominal aorta. Enteric drainage was performed by side-to-side anastomosis between the duodenum of donors and that of recipients. Results: Fifty experiments were performed. The successful rate of transplantation which restored the recipients euglycemia were 78%. Conclusion: This model of pancreaticoduodenal transplantation in rats was stable and reliable, which was in accordance with the trend of clinical pancreas transplantation and could be applied for further scientific research.
Keywords：pancreaticoduodenal transplantationratmodel
Publication Date：2004-10-31
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 308-311 )