Transcatheter to Close the Patent Ductus Arteriosus and Atrial Septal Defects in Children

Abstract：Objective: To evaluate the therapeutic efect, safety and complications of transcathetering Amplatzer device in the closure of patent ductus arteriosus ( PDA ) and atrial septal defects ( ASD ) in children. Methods: Patients with PDA ( n= 25 ) and ASD ( n =16), confirmed by echocardiography, were treated by transcatheterization. Amplatzer occluder device was placed by the transcatheterization with the image support of X-ray and transthoracic echocardiography (TTE) . The TTE , ECG and X-ray examination were engaged to evaluate the therapeutic results on the time points of 24 h, 1, 3, 6, 12 months after the operation, and all these cases were engaged to the follow-up examination. Results: The cardioangiographic diameter was 13.0-28.0 mm ([19.3 ±4.9] mm) inASD and 2.0-7.7 mm ([3.9± 1.5] mm)in PDA. The diameter of the Amplatzer occluder selected were 13.0- 30.0 mm ( [ 20.6 ± 5.1]mm) in ASD and 4. 0- 12.0 mm ( [6.6 ± 1.9] mm) in PDA , respectively. All the Amplatzer occluders were placed successfully. There were no complications during and after the operation.Very small residual shunt was still found soon after the operation in 10 cases, and there were no residual or recanalization after three months of the operation. The pulmonary artery pressure and heart size were significantly decreased in follow-up examination. Conclusion: Transcathetering closure with Amplatzer device is an effective, simple and safe technique in the treatment of ASD and PDA in children.