Effect of lung protective ventilation strategy on postoperative pulmonary complica-tions in patients during anesthesia recovery period
ZHAO Yanhua
LYU Xia
LI Lijuan
XIE Mingyan
Abstract：Objective To explore the application of lung protective ventilation strategy(LPVS)during the anesthesia recovery period and analyze its impact on postoperative pulmonary complications(PPCs)within 24 h after surgery.Methods Eighty patients,aged 18-75 years old,with a body mass index(BMI)of 18-28 kg/m2,of American Society of Anesthesiologists(ASA)Physical Status classifi-cation Ⅰ-Ⅲ,undergoing elective surgery under general anesthesia with endotracheal intubation from July 2023 to July 2024 were ran-domly divided into an LPVS group(observation group,n=40)and a conventional ventilation group(control group,n=40).The LPVS group received low tidal volume(6-8 mL/kg,predicted body weight),individualized PEEP(5-8 cmH2O,titrated based on optimal oxygenation),and hourly lung recruitment maneuvers(30 s duration,30 cmH2O pressure).The control group received VT 10-12 mL/kg and fixed PEEP 0 cmH2O.Respiratory mechanics during the recovery period(from extubation to discharge from the post-anesthesia care unit)and the incidence of PPCs within 24 h postoperatively were compared.Results The observation group showed significantly lower VT(365.95±8.84 vs 395.87±9.06 mL),airway resistance(5.53±2.09 vs 9.11±2.78 cmH2O/s),and mechanical ventilation duration(50.54±11.04 vs 75.35±8.55 min)compared to the control group(P＜0.05).The overall incidence rate of PPCs was signif-icantly reduced in the observation group(10％vs 35％,P＜0.001).Conclusion The application of LPVS during the anesthesia recov-ery period optimizes respiratory mechanics,shortens recovery time,and reduces the risk of PPCs within 24 h postoperatively.
Keywords：lung protective ventilation strategyanesthesia recovery periodpostoperative pulmonary complicationslow tidal volumepositive end-expiratory pressure
Publication Date：2025-06-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 208-211 )