Clinical observation of erector spinae plane block guided by bupivacaine liposome in thoracoscopic surgery

LI Zhengyang; ZHOU Lulu; JIA Ning; ZHAN Weiwei

doi:10.3969/j.issn.2096-2681.2024.05.007

Abstract：Objective To compare the analgesic effect and duration of bupivacaine liposome and ropivacaine in erector spinae plane block(ESPB)after thoracoscopic surgery.Methods A total of 60 patients of either gender,aged 18-65 years,with BMI less than 30 kg/m2,ASA Ⅰ-Ⅲ,receiving thoracoscopic pulmonary lobectomy in Gezhouba Central Hospital of Sinopharm,from February to May 2024 were selected and randomly divided into the bupivacaine liposome group(n=30)and the ropivacaine group(n=30).Patients in both groups were received ESPB under the guidance of ultrasound under lateral position.The bupivacaine liposome group received bupiva-caine liposome 266 mg combined with normal saline for a total of 30 mL,and the ropivacaine group received ropivacaine 100 mg combined with normal saline for a total of 30 mL.Sufentanil was prepared with PCIA standard body weight for postoperative analgesia in both groups without setting background dose.The first compression time of PCA time,times of compressions and times of relief analgesia were recorded.The resting and movement NRS pain scores and the occurrence of postoperative complications was recorded at 2 h(T,),6 h(T2),12 h(T3),24 h(T4),36 h(T5),48 h(T6)and 72 h(T7)postoperatively.Results Compared with the ropivacaine group,the times of PCA compression and relief analgesia of the bupivacaine liposome group were less(P＜0.05);the resting and movement NRS pain scores were lower at T3,T4,T5,T6,T7(P＜0.05);and the postoperative complications of the group LB was less(P＜0.05).Conclusion Bupivacaine liposomes can be used safely and effectively for postoperative analgesia in thoracic surgery,and can provide longer analgesia effect than ropivacaine.