Meta analysis of the effect of different endotracheal suction timing on endotracheal extubation in patients under general anesthesia
WANG Xiuli
LIU Xiaoli
SUN Liang
HE Miao
Abstract：Objective To compare the effects of different endotracheal suction timing on endotracheal extubation in patients under general anesthesia.Methods The database of the PubMed,Web of Science,EMBASE,Cochrane Library CNKI,Wanfang Data,VIP database and SinoMed were screened for randomized controlled trials on the effects of different suction timing on endotracheal extubation in patients under general anesthesia.The Meta-analysis was performed using RevMan5.3 software and the retrieval date from January 2000 to October 2022.The Cochrane quality evaluation tool was used to evaluate the literature quality.A total of 1090 patients were included in 9 randomized controlled trials,which were divided into the control group(n=542)and the experimental group(n=548).Results Meta-analysis results showed that,compared with the control group,patients in the experimental group had more stable post-extubation blood pressure[MD=-4.34,95％CI(-5.25,-3.42),P＜0.01]and heart rate[MD=-6.26,95％CI(-6.99,-5.54),P＜0.01];the incidence of cough[RR=0.40,95％CI(0.23-0.69),P＜0.01]was low;the oxygen saturation after extubation was higher,the difference was statistically significant[MD=4.26,95％CI(3.52-5.00),P＜0.01].Conclusion Endotracheal suction under deep anesthesia are better than endotracheal suction after waking in reducing the fluctuation of heart rate and blood pressure,and reducing the occurrence of cough and hypoxia.
Keywords：endotracheal suctiongeneral anesthesiatracheal intubationextubationMeta analysissystematic review
Publication Date：2024-10-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 254-259 )