Research progress in the relationship between immune dysfunction and gut microbiota dysbiosis of idiopathic nephrotic syndrome in children
ZHU Yu
WANG Jingjing
ZHU Yueling
ZHANG Yao
Abstract：Idiopathic nephrotic syndrome(INS)in children is a type of primary glomerular disease caused by a variety of causes.Recent research has highlighted the pivotal roles of immune dysfunction and gut microbiota imbalance in its development.Regulatory T cell dysfunction is key in INS progression,and changes in gut microbiota composition and its metabolic byproducts are closely tied to immune system disruption.This study aims to perform a systematic review of the relationship between immune dysfunction and gut microbiota dysbiosis in INS children.
Keywords：Idiopathic nephrotic syndromeImmune functionGut microbiotaChildren
Publication Date：2024-10-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 796-801 )