Clinical values of serum IL-24 and IL-6 concentration detection in children patients with Burkitt lymphoma
MA Ming
ZHAO Riyang
ZHU Xiuli
YANG Xingxiao
ZHAO Lianmei
SHAN Bao'en
Abstract：To investigate the clinical values of serum IL-24 and IL-6 concentration in children patients with Burkitt lymphoma, we analyzed the association of serum IL-24 and IL-6 concentration with clinicopathological parameters in 45 cases of children patients with Burkitt lymphoma by using ELISA assays. Data showed that the IL-24 level in serum of patients with Burkitt lymphoma was significantly lower than that of patients in normal control groups (P<0. 01). Both IL-24 and IL-6 levels in serum were associated with the bone marrow metastasis status and clinical stage of Burkitt lymphoma patients (P<0. 01), while were not related to gender, age and the IPI index (P>0. 05). These findings suggested that the concentration of IL-24 and IL-6 proteins in serum are closely correlated with the bone marrow metastasis status and clinical stage in children patients with Burkitt lymphoma. Thus, detection of the serum IL-24 and IL-6 concentration may provide the evidence for clinical therapy of Burkitt lymphoma as auxiliary diagnosis.
Keywords：Burkitt lymphomaIL-24IL-6Tumor marker
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 524-528 )