The progress in functions and mechanism of Nogo-B in inflammatory diseases
HOU Pengfei
YAO Yuan
XIN Haoran
DENG Qiyue
Abstract：Nogo-B,an endoplasmic reticulum transmembrane protein,belongs to the family of reticular proteins,widely expressed on cell membrane systems in various organs.Recent studies on the molecular structure and novel functions of Nogo-B have shown that Nogo-B plays a significant role in the pathogenesis of atherosclerosis,alcoholic liver disease,acute lung injury and other inflammatory diseases.Further studies on the mechanisms of Nogo-B would contribute to identify new targets for clinical therapeutics and provide evidences for treatment of various inflammatory diseases.
Keywords：Nogo-BInflammationAtherosclerosisAlcoholic liver diseaseAcute lung injury
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 265-268 )