Immune molecules involved in the regulation of CD4+ Treg
WANG Ning
JIN Jingyi
CHEN Lihua
Abstract：CD4 + Treg cells are essential to maintain immune homeostasis and protection against autoimmunity.The immunosuppressive function of CD4 + Treg cells are closely related to many diseases or pathological state,such as autoimmune diseases,tumors,inflammatory immune response and post-transplant rejection,etc.Study of Treg cells and associated immune negative regulatory mechanisms are important for the prevention and treatment of autoimmune diseases,the regulation of anti-inflammatory and anti-tumor immune responses.In this paper,we will review the immune-regulatory effects of transmembrane molecules,transcription factors and cytokines on CD4+Treg cells in detail.
Keywords：CD4+ regulatory T cellTranscription factorsTransmembrane molecules
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 73-79 )