Research progress of new immune adjuvant in allergen-specific immune tolerance therapy
LIN Chuanchuan
SONG Zhiqiang
LUO Na
Abstract：Allergen-specific immunotherapy (SIT) is the mainly effective way to originally treat allergic disease till now.It relies upon gradually increasing doses of specific allergens to establish long terms of allergen-specific tolerance,and the most commonly used ways include subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) by using desensitization agents.Immune adjuvant (IA) is a kind of immunoenhancement agent which can be naturally or artificially synthesized.IA has widely used to prepare desensitization agents,not only because of its effects on increasing therapeutic efficiency,but also on decreasing the doses of desensitization agents.We emphasize the types,mechanism and clinical usages of the new immune adjuvants till today in this review,in order to give evidences to the important theoretical value and practical significances for the preparation and clinical uses of desensitization agents.
Keywords：Allergen-specific immunotherapyImmune adjuvantAllergic diseases
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1003-1008 )