Effects of different splenic preserving techniques on immune function in patients with traumatic splenic rupture and hemorrhagic shock

ZHANG Wei

doi:10.13431/j.cnki.immunol.j.20170161

Abstract：To study the effects of different spleen preserving operation for traumatic splenic rupture and hemorrhagic shock on immune function,and its clinical effect,85 cases of traumatic spleen rupture and hemorrhagic shock patients treated with spleen repair (40 cases,group A) or splenic artery embolization (45 cases,group B) in our hospital from January 2015 to February 2017 were selected as the research objects,and 40 healthy blood donors were selected as group C.Patients of groups A and B were compared in operation time,hospitalization time,blood transfusion volume,the success rate of rescue,and the incidence of complications.At the same time,the levels of T lymphocytes were compared among groups of A,B,C.Data showed that the operation time,hospitalization time,blood transfusion volume of group B were significantly lower than those of group A (P＜0.01),and the success rate of rescue in group B was significantly higher than that of group A (x2=4.13,P=0.04);the total incidence of complications in group B (4.44％) was significantly lower than that of group A (25％) (x2=7.38,P＜0.01).Furthermore,the CD3+,CD4+,CD8+,CD4+/CD8+ levels of groups A and B were obviously lower than those of group C (P＜0.05),while the CD3+,CD4+,CD4+/CD8+ levels in group B at 15 d and 30 d psot operation were significantly higher that those in group A (P＜0.01).In conclusion,splenic artery embolization in the treatment of traumatic splenic rupture with hemorrhagic shock of high safety,simple operation,less trauma,can reduce the incidence of complications and improve success rate of rescue,and recover postoperative immune function rapidly,thus which is worthy of clinical promotion.