Research advances of IL-33 and its receptor ST2 in sepsis
HAN Li
LI Peiwu
FU Xu
Abstract：Sepsis,characterized with high mortality and high treatment cost,become a serious threat to human health.Immune imbalance plays an important role in the development of sepsis,however immunosuppression in sepsis and molecular mechanism remains unclear.Recent studies suggested that IL-33,a new member of IL-1 family,and its receptor ST2 are new immune regulatory factors in the development of sepsis.This article will provide a review and summary on the roles of IL-33 and ST2 in sepsis development.
Keywords：SepsisIL-33ST2
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 824-828 )