Research advances of myeloid inhibitory cells in tumor microenvironment
HAO Wenbin
XIANG Fenfen
LIU Qiaoli
YUE Honghong
KANG Xiangdong
Abstract：Myeloid-derived suppressor cells (MDSCs) are one of the main components of tumor microenvironment.These cells are characterized by potent immunosuppressive activity.MDSCs interact with tumor ceils through a high degree of cascade effect,leading to tumor cells further development and escaping from the immune system surveillance.The essence of cancer immune therapy is to promote the immune system to attack tumor cells.This paper focuses on MDSCs assisting tumor immune escape,the mechanism of tumor recruitment of MDSCs,and the regulation of traditional Chinese medicine on MDSCs.
Keywords：Myeloid-derived suppressor cellsImmune suppressiveCascade effects
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 729-732 )