Panel reaction antibody and organ transplantation
LUO Min
XIAO Lulu
Abstract：Panel reltction antibody(PRA)were proven as the most important factor in transplantation.Investigations demonstrated that the generation of rejection was mediated by humoral immunity.PRA analysis reflects the sensitization status of human leucocyte antigen (HLA)in recipient pretransplant,predicts the prevalenee of rejection,and hints the transplant loss posttransplant.The utilized of PRA sig-nificaJltly depressed the incidence of organ transplantation.Recently,more researchers turned their interest to the effect and prospectlve ap-plication of PRA,especially donor-specific antibodies(DSA),in organ transplantation such as kidney transplantation,cardiac transplantation,and lung transplantation is warrant being investigated. This article reviews the association of PRA against organ transplantation.
Keywords：PRATransplantationRejectionDSA
Publication Date：2010-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 167-170 )