Enhancement of Cordyceps taii polysaccharide and Cordyceps pru inosa polysaccharide on cellular immune function in vitro
Abstract：Objective Cordyceps polysaccharide has important effects oninhibition of tumor, radio-protection and enhancement of immune response. In this paper ,the effect of Cordyceps taii polysaccharide (CDP1) and Cordyceps pruinosa polysaccharide(CPP1) on cellular immunological function of splenic T cell and MΦ phagocytosis in mice was investigated. Methods The proliferation of lymphocytes was measured with MTT assay, the activity of CTL cells was detected by colorimetric method of neutral red, MΦ phagocytosis was measured with colorimetric method of malachite green.Results Not only was the proliferation of activated splenic T cell enhanced, but also proliferation of activated splenic T cell in immune-inhibited mice was restored with CDP1 and CPP1 in vitro. It could promote CTL cytotoxity and M Φ phagocytosis in normal mice and immune inhibited mice.Conclusion Cordyceps taii polysaccharide and Cordyceps pruinosa polysaccharide can enhance the cellular immune functions in vitro.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 189-191 )