Study of gastroenteric mucosa immune responses in Balb／c mice by oral immunization with helicobacter pylori
LU Dong-shui
YU Chang-qing
ZOU Quang-ming
Abstract：Objective To study the mucosa immune responses of gastric and intestinal mucosa in Balb／c mice administered orally with Hp sonicate and mucosal adjuvant（LT）．Methods The changes of antigen specific AFC in gastric and intestinal mucosa were detected by ELISPOT assay． Results The numbers of sIgA and IgG AFC rise significantly in PP and gastric mucosa， especially the numbers of sIgA-AFC， significant differences were observed between two immunized groups and the control． Conclusions Locally synthesized specific sIgA antibodies contribute to immunity against gastric helicobacter infection．
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 107-109 )